Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System

Abstract

Chiral compounds such as alanine amino acid and s-aminethylated L-cystiene derivatized with chiral reagents such as Marfey's reagents, 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosylisothiocyanate (GITC) and 2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosylisothiocyanate (BGIT), were achieved and separated by optimizing good methods using high performance liquid chromatography.

Keywords: Derivatization, amino acid, chiral reagent, HPLC

Cite this Article

Khlafulla Abdulrahim M, Maga Rajab A, Elmessmary Mohamad F. Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System. Research & Reviews: A Journal of Pharmacology. 2016; 6(2): 39–43p.