Effect of Dimethyl Sulfoxide Extract on Different Parts of a Medicinal Plant:Euphorbia hirta L. Against Escherichia coli and Staphylococcus aureus

Abstract

Euphorbia hirta has been widely used by tribal as traditional medicine in the treatment against infectious pathogens. Euphorbia hirta Linn. is a perennial herb belonging to the family Euphorbiaceae. It is a potent medicinal plant and has established its sedative and anxiolytic activity. It has analgesic, antipyretic, anti-inflammatory, antidepressant for blood pressure, antihypertensive and antioxidant properties. Effect of dimethyl sulfoxide extract on different parts (leaf, bud and stem) of Euphorbia hirta L. were examined using agar disc diffusion method against Escherichia coli and Staphylococcus aureus. Maximum in vitro inhibition of tested bacteria E. coli was scored in leaf extract of E. hirta using dimethyl sulfoxide as solvent which offers the diameter of inhibition zone (DIZ) of 20 mm and zone of inhibition area (ZIA) of 471.00 mm². In case of S. aureus, both leaves and buds extracts offered same DIZ of 15 mm and ZIA of 294.38 mm².

Keywords: solvent, leaf extracts, E. hirta, Escherichia coli, Staphylococcus aureus

Cite this Article

Kumari I. Effect of Dimethyl Sulfoxide Extract on Different Parts of a Medicinal Plant—Euphorbia hirta L. against Escherichia coli and Staphylococcus aureus. Research & Reviews: A Journal of Biotechnology. 2015; 5(2): 30–33p.