Synthesis and Biological Screening of Some New3,5-Disubstituted-2-Isoxazolines

Abstract

Series of novel 3,5-disubstituted-2-isoxazolines have been synthesized via 1,3-dipolarcycloaddition reactions. All the synthesised compounds were confirmed by spectroscopic methods evaluated for their antimicrobial activity and were compared with the standard drugs. The compounds demonstrated potent to weak antimicrobial activity.

Keywords: Isoxazolines, antimicrobial activity, chloramine-T